Definition of MAO inhibitorMAO inhibitor: One of a family of medications (brand names: Aurorex, Nardil, Parnate) that act to limit the activity of monoamine oxydase (MAO) in the nervous system. MAOIs are prescribed to treat depression, anxiety, migraine, and selected other conditions in patients who are not responsive to other medications. They interact with many over-the-counter medications and some foods, so patients taking MAOIs must be educated about what to avoid and must follow a restricted diet. Last Editorial Review: 3/19/2012
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