Definition of Cephalothoracic lipodystrophyCephalothoracic lipodystrophy: A disorder characterized by painless symmetrical diffuse deposits of fat beneath the skin of the neck, upper trunk, arms, and legs. The condition is genetic and is inherited as an autosomal dominant trait. Also known as multiple symmetrical lipomatosis, Launois-Bensaude syndrome, Madelung disease, and familial benign cervical lipomatosis. Last Editorial Review: 3/19/2012
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