Definition of Cardiac outputCardiac output: The amount of blood the heart pumps through the circulatory system in a minute. The amount of blood put out by the left ventricle of the heart in one contraction is called the stroke volume. The stroke volume and the heart rate determine the cardiac output. A normal adult has a cardiac output of 4.7 liters (5 quarts) of blood per minute. Last Editorial Review: 3/19/2012
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