Definition of Diarrhea and dermatitis, zinc deficiency
Diarrhea and dermatitis, zinc deficiency: Among the
consequences of zinc deficiency, dermatitis (skin inflammation) and
diarrhea are particularly prominent features.
A genetic disease called acrodermatitis enteropathica in which
there is impaired zinc uptake from the intestine is, in fact,
characterized by the simultaneous presence of dermatitis (skin
inflammation) and diarrhea. The skin on the cheeks, elbows and knees
and the tissues about the mouth and anus are inflamed. There is
balding of the scalp, eyebrows and eyelashes. Wound healing is
delayed. And there are recurrent bacterial and fungal infections due
to immune deficiency. The key laboratory finding in acrodermatitis
enteropathica is an
abnormally low
blood zinc level reflecting the impaired zinc uptake. Treatment with
zinc is curative.
Last Editorial Review: 11/10/1998 4:41:00 PM
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