Definition of GlucosamineGlucosamine: A molecule derived from the sugar glucose by the addition of an amino group. Glucosamine is a component of a number of structures, including the blood group substances and cartilage. Glucosamine is currently in use as a nutritional supplement (often in combination with chondroitin) and is touted as a remedy for arthritic symptoms. Last Editorial Review: 3/19/2012
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