Definition of AcetoneAcetone: A volatile liquid used as an industrial solvent. Acetone is also one of the ketone bodies that is formed when the body uses fat instead of glucose (sugar) for energy. The formation of acetone is usually a sign that cells lack insulin or cannot effectively use the insulin that is available, as occurs in diabetes. Acetone is excreted from the body in the urine. Last Editorial Review: 3/19/2012
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