Definition of Heberden nodeHeberden node: A small fixed bump on the finger, usually at the last joint of the finger, Heberden's node is a calcified spur of the joint (articular) cartilage and is a sign of osteoarthritis. Named for the English physician William Heberden (1710-1801) who made a number of celebrated medical discoveries (including angina). Last Editorial Review: 6/14/2012
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