Definition of Speckled iris

Speckled iris: Due to little white (or lightly colored) spots that are slightly elevated on the surface of the iris. These spots, arranged in a ring concentric with the pupil, occur in normal children but are far more frequent in Down's syndrome (trisomy 21). They were described in 1924 by Thomas Brushfield, are called Brushfield's spots, and are due to aggregation of a normal iris element (connective tissue).


Last Editorial Review: 8/28/2013

Search MedTerms:


Back to MedTerms online medical dictionary A-Z List
Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.