Definition of Syndrome, reflex sympathetic dystrophy (RSDS)Syndrome, reflex sympathetic dystrophy (RSDS): A condition that features a group of typical symptoms, including pain (often "burning" type), tenderness, and swelling of an extremity associated with varying degrees of sweating, warmth and/or coolness, flushing, discoloration, and shiny skin. Last Editorial Review: 6/14/2012
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