Definition of Syndrome, Martin-Bell

Syndrome, Martin-Bell: Better known as the fragile X syndrome, the most common heritable form of mental retardation. Fragile X syndrome is due to mutation (changes) at the fragile X site and so perforce is X-linked (carried on the X chromosome). Although it is usually more severe in males than females, the syndrome is due to a dynamic mutation (a trinucleotide repeat) that can change in length and hence in severity from generation to generation, from person to person, and even within a given person. The fragile X syndrome is known as the Martin-Bell syndrome in honor of their discovery of it in 1943.


Last Editorial Review: 6/14/2012

Search MedTerms:


Back to MedTerms online medical dictionary A-Z List
Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.


STAY INFORMED

Get the Latest health and medical information delivered direct to your inbox!