Definition of Syndrome, BrownSyndrome, Brown: An ophthalmology (eye) problem. Brown syndrome is an abnormality that is present at birth (congenitally) and is characterized by an inability to elevate the eyeball when trying to move the eyeball to the outside. Brown syndrome can also occur because of other conditions which affect the normal function of the eye muscles. The syndrome is named for the American ophthalmologist Harold W. Brown. Last Editorial Review: 6/14/2012
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