Definition of Spleen

Spleen: An organ that is located in the upper-left part of the abdomen, not far from the stomach, that produces lymphocytes, which are important elements in the immune system. The spleen is the largest lymphatic organ in the body. The spleen also filters blood, serves as a major reservoir for blood, and destroys blood cells that are aged (or abnormal, as in the case of sickle cells).


Last Editorial Review: 3/19/2012

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