Definition of Psychosis, schizophreniaPsychosis, schizophrenia: The most chronic and disabling of the major mental illnesses. Schizophrenia may be one disorder, or it may be many disorders, with different causes. Because of the disorder's complexity, few generalizations hold true for all people who are diagnosed as schizophrenic. Last Editorial Review: 6/14/2012 Back to MedTerms online medical dictionary A-Z List 
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