Definition of PedigreePedigree: In medicine, a family health history that is diagrammed with a set of international symbols to indicate the individuals in the family, their gender, their relationships to one another, those with diseases, and other data. A pedigree is a basic tool of clinical genetics that is used to determine that a disease is genetic, track the transmission of the disease, and estimate risks to the patient, other family members, and the unborn from a genetic disease. Last Editorial Review: 3/19/2012
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