Definition of Functional hemispherectomyFunctional hemispherectomy: A functional hemispherectomy is a variation of a hemispherectomy, a radical procedure in which one entire hemisphere, or one half of the brain, is removed. With a functional hemispherectomy, one hemisphere is disconnected from the rest of the brain, but only a limited area of brain tissue is removed. This surgery generally is limited to children younger than 13 years old who have one hemisphere that is not functioning normally. Last Editorial Review: 6/14/2012
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