Definition of Onycho- (prefix)Onycho- (prefix): Pertaining to the nails. Examples of medical terms involving "onycho-" include onychodystrophy (abnormal growth and development of the nails), onychomycosis (fungal infection of the nails), onychogryposis (abnormally curved nails) and onychoosteodysplasia (malformation of bones and nails). Last Editorial Review: 6/14/2012
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