Definition of Nitrosoureas

Nitrosoureas: A group of cancer drugs called alkylating agents because they act by the process of alkylation to inhibit DNA repair. The nitrosoureas can cross the blood-brain barrier and are used to treat brain tumors. The nitrosoureas include carmustine (BCNU), lomustine (CCNU) and semustine.


Last Editorial Review: 6/14/2012

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