Definition of GermGerm: 1. A cell or group of cells (called a primordium) capable of developing into an organ, a part or an organism in its entirety. Eggs and sperm are germ cells. Germ is a deceptively simple word that came to us from Latin germen, meaning a sprout, bud, or offshoot. In all of its meanings, the term germ retains the idea of developing into something more mature. Last Editorial Review: 6/14/2012
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