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Definition of Hybrid

Hybrid: The word "hybrid" has a number of different biomedical meanings.

In transmission genetics, a hybrid is the result of a cross between two genetically dissimilar parents. The offspring of unlike parents. If the parents are sufficiently dissimilar, the hybrid may be sterile (for example, in the crossing of horse and donkey to produce a mule).

In cell genetics, a hybrid cell is one that contains components from one or more genomes (other than zygotes and their derivatives). Hybrid cells may be formed by several techniques including cell fusion, the fusion of two or more cells.

In molecular genetics, a hybrid DNA molecule is a DNA molecule with strands of different origin.


Last Editorial Review: 7/9/2000

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