Definition of Heterochromatin, facultativeHeterochromatin, facultative: Heterochromatin that need not always be heterochromatic but which has the faculty to return to the normal euchromatic state. The inactive X chromosome is made up of facultative heterochromatin. When a woman transmits that X to a son, it reverts to euchromatin and genetic activity. Last Editorial Review: 6/14/2012
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