Definition of Gareis-Mason syndrome

Gareis-Mason syndrome: An inherited (genetic) syndrome with characteristic features including (1) neurologically: mental retardation and aphasia (lack of speech); (2) limbs: adducted (clasped) thumbs, absent extensor pollicis longus and/or brevis muscles to the thumb, shuffling gait, and leg spasticity; (3) growth: small body size; (4) skeleton: lumbar lordosis (sway back). The syndrome is inherited as an X-linked trait and so affects mainly boys. Alternative names include MASA syndrome (MASA stands for mental retardation, aphasia, shuffling gait, and adducted thumbs), clasped thumb and mental retardation, congenital clasped thumb with mental retardation, and adducted thumb with mental retardation.


Last Editorial Review: 8/28/2013

Search MedTerms:


Back to MedTerms online medical dictionary A-Z List
Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.


STAY INFORMED

Get the Latest health and medical information delivered direct to your inbox!