Definition of Amyotrophic lateral sclerosis 3Amyotrophic lateral sclerosis 3: ALS3. An adult-onset form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner and caused by mutation in a gene on chromosome 18q21. Last Editorial Review: 6/14/2012 Back to MedTerms online medical dictionary A-Z List 
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