Definition of Amyotrophic lateral sclerosis 2Amyotrophic lateral sclerosis 2: ALS2. A juvenile-onset form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal recessive manner and caused by mutation in the gene encoding alsin on chromosome 2q33. Last Editorial Review: 6/14/2012 Back to MedTerms online medical dictionary A-Z List 
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