Definition of PLP1

PLP1: The gene encoding proteolipid protein, or lipophilin, the primary constituent of myelin. The PLP1 gene is on the X chromosome in band Xq22. Mutations in PLP1 cause Pelizaeus-Merzbacher disease (PMD) and X-linked spastic paraplegia 2 (SPG2).


Last Editorial Review: 6/14/2012

Search MedTerms:


Back to MedTerms online medical dictionary A-Z List
Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.


STAY INFORMED

Get the Latest health and medical information delivered direct to your inbox!