Definition of PrimordiumPrimordium: In embryology, organ or tissue in its earliest recognizable stage of development. Take, for example, the thyroid primordium. The plural is primordia. Borrowed directly from the Latin primordium (to begin), derived from the Latin words primus (first) + ordiri (to begin). Known also as the anlage or rudiment. Last Editorial Review: 9/20/2012
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