Definition of 5-HT1A5-HT1A: A type of receptor for serotonin. The gene that encodes this receptor has been named HTR1A and is located on chromosome 5 in region 5q11.2-q13. Serotonin (also known as 5-hydroxytryptamine) is an important neurotransmitter within the central nervous system. After it is released by a neuron, serotonin activates receptors located on nearby neurons. These receptors include 5-HT1A. 5-HT1A stands for 5-beta hydroxytryptamine receptor 1. Last Editorial Review: 6/14/2012
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