Definition of Bernstein testBernstein test: A test to find out if heartburn is caused by acid in the esophagus, and so to diagnose GERD (gastroesophageal reflux disease). The test involves dripping a mild acid, similar to stomach acid, through a tube placed in the esophagus. Also known as esophageal acid infusion test. Last Editorial Review: 3/19/2012
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