Definition of Spindle neuron

Spindle neuron: A large neuron tapered at both ends that is only found in humans and great apes and so is thought to be a relatively recent evolutionary addition to the nervous system. Spindle neurons are confined to the anterior cingulate cortex, a region of the brain that plays a role in emotion, decision-making, and autonomic functions of the brain such as the regulation of the heart rate and blood pressure. Spindle neurons are typically lost in the course of Alzheimer disease.


Last Editorial Review: 6/14/2012

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