Definition of AnorgasmiaAnorgasmia: Failure to achieve orgasm (climax) during sexual intercourse. Anorgasmia has many causes, including stress, anxiety, depression, fatigue, worry, guilt, fear of painful intercourse, fear of pregnancy, the undesirability of a partner, the undesirability of a setting, and the use of alcohol or prescription or illicit drugs. Last Editorial Review: 3/19/2012
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