Definition of CholecystokininCholecystokinin: Abbreviated CCK. A polypeptide hormone that stimulates the contraction of the gallbladder with release of bile and the secretion of pancreatic enzymes into the small intestine. CCK is secreted by cells lining the upper intestine and by the hypothalamus. Hypothalamic cholecystokinin is a neurotransmitter. Called also pancreozymin. Last Editorial Review: 6/14/2012
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