Definition of BlepharospasmBlepharospasm: The involuntary, forcible closure of the eyelids. The first symptoms may be uncontrollable blinking. Only one eye may be affected initially, but eventually both eyes are usually involved. The spasms may leave the eyelids completely closed, causing functional blindness even though the eyes and vision are normal. Blepharospasm is a form of focal dystonia. Last Editorial Review: 3/19/2012
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