Definition of Citrulline

Citrulline: A non-standard amino acid that is not normally present in protein. Citrulline is created in the body as an intermediate in the conversion of the amino acid ornithine to arginine in a metabolic pathway called the urea cycle.

Citrulline was first isolated from watermelon. The term citrulline was coined in 1930 from citrullus, the Latin name of the watermelon.


Last Editorial Review: 6/14/2012

Search MedTerms:


Back to MedTerms online medical dictionary A-Z List
Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.