Definition of AmpullaAmpulla: In anatomy, a sac-like enlargement of a canal or duct. The ampulla of Vater is the enlargement of the ducts from the liver and pancreas at the point where they enter the small intestine. Ampulla in Latin means flask. An ampulla was a flask used in ancient Rome to hold ointment, perfume, and wine. Last Editorial Review: 6/14/2012
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