Definition of Fatal familial insomnia

1. Causes of Fatigue Slideshow Pictures
2. Take the Sleep Quiz
3. Foods That Help or Harm Your Sleep Slideshow Pictures

Fatal familial insomnia: Abbreviated FFI. An hereditary prion disease characterized by disrupted sleep (insomnia), motor abnormalities (myoclonus, ataxia, dysarthria, dysphagia, and pyramidal signs), and hyperactivation of the autonomic nervous system. Due to a missense mutation at codon 178 of the prion protein gene on chromosome 20. A sporadic form of fatal insomnia is also known.

Need help identifying pills and medications?
Use the pill finder tool on RxList.