Definition of Catechol-O-methyltransferase

1. Bad Bugs and Their Bites Slideshow
2. Heartburn: Foods to Eat and Avoid Slideshow
3. Understanding Multiple Sclerosis Slideshow

Catechol-O-methyltransferase: COMT. An enzyme that catalyzes the degradation of catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. COMT is also important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. A genetic polymorphism (a common normal variant) in COMT contributes to the responses to pain and stress.

Need help identifying pills and medications?
Use the pill finder tool on RxList.