Definition of Melanoma, ocularMelanoma, ocular: A rare type of malignant melanoma that arises from a structure within the eye. The most common sites for ocular melanoma are the choroid, the ciliary body, and the iris. The tumor may metastasize (spread), most often to the liver. Ocular melanoma tends to occur after age 40. Last Editorial Review: 3/19/2012
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