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Definition of IgE

IgE: Immunoglobulin E, a class of immunoglobulins that includes the antibodies elicited by an allergic substance (allergen). A person who has an allergy usually has elevated blood levels of IgE. IgE antibodies attack and engage the invading army of allergens. The E in IgE stands for erythema (redness).

Last Editorial Review: 2/4/2004

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