Definition of Optic gliomaOptic glioma: A rare, most commonly benign tumor on the optic nerve or the optic chiasm (the crossing of the two optic nerves). Optic gliomas cause pressure and destruction of normal optic nerve tissue. They are most common in children and teens. Optic gliomas are strongly associated with neurofibromatosis (NF1). Last Editorial Review: 3/30/2012
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