Definition of Chromosome 5q- syndrome

Chromosome 5q- syndrome: A blood disorder due to the loss of part of the long (q) arm of chromosome 5 in myeloid (bone marrow) cells, causing refractory (treatment-resistant) anemia, and myelodysplastic syndrome that is generally associated with a good prognosis but on occasion may lead to acute myeloid leukemia (AML). The immune modulating lenalidomide (Revlimid) is beneficial in male patients with the 5Q- syndrome and may reduce transfusion needs. It does lower white blood cells and platelet counts and is not a curative option.


Last Editorial Review: 9/20/2012

Search MedTerms:


Back to MedTerms online medical dictionary A-Z List
Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.


STAY INFORMED

Get the Latest health and medical information delivered direct to your inbox!