Definition of Weaver's bottomWeaver's bottom: Inflammation of the bursa that separates the gluteus maximus muscle of the buttocks from the underlying bony prominence of the bone that a person sits on (ischial tuberosity). Weaver's bottom is a form of bursitis that is usually caused by prolonged sitting on hard surfaces that press against the bones of the bottom or midbuttocks. Also known as ischial bursitis. Last Editorial Review: 3/19/2012
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