Definition of Absence seizureAbsence seizure: A seizure that takes the form of a staring spell. The person suddenly seems to be "absent." An absence seizure involves a brief loss of awareness, which can be accompanied by blinking or mouth twitching. Absence seizures have a very characteristic appearance on an electroencephalogram (EEG). Also called a petit mal seizure. Last Editorial Review: 6/14/2012
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