Definition of AutologousAutologous: In blood transfusion and transplantation, a situation in which the donor and recipient are the same person. Patients scheduled for non-emergency surgery may be autologous donors by donating blood for themselves that will be stored until the surgery. An autologous graft is a graft (such as a graft of skin) that is provided for oneself. Last Editorial Review: 3/19/2012
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