Definition of ThioxantheneThioxanthene: One of a group of drugs with antipsychotic activity which act by blocking postsynaptic (after-the-nerve) receptors for dopamine (a chemical that nerves use to communicate with one another) in the brain. Examples include: thiothixene (brand name: Navane), chlorprothixene (Remeron) and flupenthixol. Last Editorial Review: 6/14/2012
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