Definition of Muscular dystrophy, limb-girdleMuscular dystrophy, limb-girdle: A form of muscular dystrophy (MD) that may begin in childhood or any time later, with slowly progressive weakness and wasting of the muscles in the hips or shoulders. Limb-girdle MD is caused by a number of genetic defects and can affect both males and females. Last Editorial Review: 3/19/2012
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