Definition of Mastectomy, subcutaneousMastectomy, subcutaneous: Removal of breast tissue, using a minimal incision. This type of mastectomy may be used to remove small areas of suspicious or cancerous tissue, but it can also be a cosmetic surgery procedure. For example, subcutaneous mastectomy can reduce the volume of enlarged male breasts or be part of a female-to-male sex-change procedure. Last Editorial Review: 3/19/2012
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