Definition of Intravenous immunoglobulinIntravenous immunoglobulin: A sterile solution of concentrated antibodies extracted from healthy people that is administered directly into a vein. Abbreviated IVIG. IVIG is used to treat disorders of the immune system or to boost the immune response to serious illness. Also known as intravenous gamma globulin (IGG). Last Editorial Review: 3/19/2012
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