Definition of Bone cyst, aneurysmalBone cyst, aneurysmal: A benign lesion in a bone that contains connective tissue and blood inside a thin bony shell. Aneurysmal bone cysts act like tumors and expand the bone, and they typically occur in the second decade of life. They can affect any bone in the arms, legs, trunk, or skull. Last Editorial Review: 3/19/2012
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