Definition of Palindromic rheumatismPalindromic rheumatism: A form of arthritis characterized by attacks of fleeting inflamation in and around the joints lasting hours to a few days. The fingers and knees are the most common targets. While the attacks may be painful, they typically leave no permanent joint damage. Approximately one third of affected patients develop classical rheumatoid arthritis. Last Editorial Review: 3/19/2012
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