Definition of Basal gangliaBasal ganglia: A region of the base of the brain that consists of three clusters of neurons (caudate nucleus, putamen, and globus pallidus) that are responsible for involuntary movements such as tremors, athetosis, and chorea. The basal ganglia are abnormal in a number of important neurologic conditions, including Parkinson's disease and Huntington's disease. Last Editorial Review: 3/19/2012
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